Joined the lab in January 2021
Position: Graduate student
Education: Bachelors in Dentistry,
Federal University of Para, Brazil
I am a dentist who decided to exchange a clinical career to explore my passion for science. Since my Ph.D. journey began, I had the opportunity to work with very motivating research projects and have had hands-on experience in a broad range of techniques such as cell culture, immunofluorescence approaches, gene knockdown experiments, transcription inhibition assays, molecular cloning techniques, proliferation assays, cell cycle analysis, qRT-PCR, western blotting and more. I decided to do a laboratory rotation at Dr. Ma's lab because I am interested in exploring carcinogenic viruses, and more specifically, I am interested in how Kaposi sarcoma-associated herpesvirus (KSHV) modulate cell signaling pathways in the host organism. I believe that the identification and characterization of KSHV proteins, as well as their targeted pathways on a host, may pinpoint novel approaches for treating or preventing KSHV-triggered cancer. At Dr. Ma's laboratory, I will have the opportunity to engage in many different laboratory methodologies, including CRISPR/CAS9, which is a state-of-the-art technique for genome editing. I will also learn fundamental approaches of the virology field, which is relatively new to me, and thus will broaden my background as a biomedical research assistant. I am confident that this rotation project will help me acquire meaningful experience and learning and will contribute to my path towards progressively independent researcher.
Joined the lab in October 2020
Position: Research Technician
Education: B.Sci. in Biomathematics, Florida State University
I began my undergraduate career at FSU as a physics major but switched to biomathematics when I realized I enjoyed studying nature much more than its underlying forces. Shortly after, I began volunteering in Dr. Zhu’s laboratory, where I primarily investigated ORF52 of KSHV and acquired fundamental research techniques. Under the guidance of an inspiring and amicable doctoral candidate, I grew very fond of doing research and decided to pursue this career path. In Dr. Ma’s laboratory, I will develop my skills as an effective researcher, progress our efforts in discerning the complex relationships between KSHV and innate immunity, and do my best to keep the lab organized and clean. Aside from work, my hobbies are rather geriatric and include gardening, playing chess, and (as of recently) playing Go. Feel free to challenge me to a game after work.
Joined the lab in April 2021 as a rotation student
Position: Rotation student
Education: B.Sc. Microbiology and Cell Science,
University of Florida
I received my bachelors in microbiology at the university and hope to obtain my Doctorate here as well. I am a double Gator. I am originally from the Bahamas, the land of Sun, Sand, and Sea. My research interests lie in uncovering and understanding various mechanisms and pathways related to cancer. In the past, I have had the opportunity to work on AAV viruses designed to target Medullary Thyroid Carcinoma. In Dr. Ma’s lab, I am being exposed to various techniques I believe will be useful throughout the course of my research career. When I am not doing research, I enjoy watching sitcoms and exploring the outdoors.
Joining the lab in January 2021
Position: Lab assistant
Education: Sophomore, Biochemistry,
University of Florida
I am a sophomore Biochemistry major here at UF, and I hope to also minor in Health Disparities and Mathematics. I hope to pursue a research career in Biochemistry, and my goal is to pursue graduate school, and hopefully one day, work toward a Ph.D. somewhere in the field of biochemistry. I joined Dr. Ma’s lab to learn the basics of research, learn from researchers far more experienced than me, and develop important research skills that I can hopefully use throughout my career. In my free time, I really like playing piano, painting, and writing!
Joined the lab in January 2021
Position: The Ultimate Savior and Lab manager
Education: B.Sc. in Botany, University of Glasgow, Scotland
I have worked in a diverse area in my science career, tackling everything from transgenic production, stem cell manipulation, small animal surgery and virus production to name but a few. I have trained many dozens of researchers over my career in such areas, and currently am the University trainer for the Perkin Elmer IVIS Spectrum bioluminescent / fluorescent imager. My goal is to leverage my experience to assist personnel in acquiring additional skills, to maintain the laboratory and to provide the group with regulatory compliance support as needed. Over my 20 year tenure at UF, I have developed a substantial network of resources across the UF Health Sciences Center over the years and understand the criticality of relationship building for future flexibility. My goal is to be a problem fixer and process improver; a resource that motivates, engages and is not hesitant to evolve. I am always eager to learn, improvise and innovate.
“Extended time-lapse in vivo imaging of tibia bone marrow to visualize dynamic hematopoietic stem cell engraftment” S Kim, L Lin, G A J Brown, K Hosaka3 and E W Scott. Leukemia, online 28 November 2016
"Bone marrow-derived cells home to and regenerate retinal pigment epithelium after injury." Harris JR, Brown GA, Jorgensen M, Kaushal S, Ellis EA, Grant MB & Scott EW. Invest Ophthalmol Vis Sci. 47(5):2108-13.
"Cone cell survival and downregulation of GCAP1 protein in the retinas of GC1 knockout mice." Coleman JE, Zhang Y, Brown GA, Semple-Rowland SL. Invest Ophthalmol Vis Sci. 45(10):3397-403.
"The contribution of adult hematopoietic stem cells to retinal neovascularization." Grant MB, Caballero S, Brown GA, Guthrie SM, Mames RN, Vaught T, Scott EW. Adv Exp Med Biol; 522:37-45
"Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization." Grant, MB, May, WS, Caballero, S, Brown, GA, Guthrie, SM, Mames, RN, Byrne, BJ, Vaught, T, Spoerri, PI, Peck, AB & Scott EW. Nature Medicine Jun 8(6):607-12
"Oocyte injection in the mouse." Brown GA, Corbin TJ Methods Mol Biol.180:39-70
"Rnx deficiency results in congenital central hypoventilation"; Shirasawa S, Arata A, Onimaru H, Roth KA, Brown GA, Horning S, Arata S, Okumura K, Sasazuki T, Korsmeyer SJ. Nature Genetics Mar 24(3):287-90
"Enx(Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon"; Senji Shirasawa, Anne Marie R. Yunker, Kevin A. Roth, Gary A. J. Brown, Susan Horning and Stanley J. Korsmeyer. Nature Medicine Vol.3 (6), pp. 646-650
"Altered Hox expression and segmental identity in Mll-mutant mice"; Benjamin D. Yu, Jay L. Hess, Susan E. Horning, Gary A. J. Brown and Stanley J. Korsmeyer. Nature Vol.378 pp. 505-508
"Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death"; C. Michael Knudson, Kenneth S. K. Tung, Warren G. Tortellotte, Gary A. J. Brown and Stanley J. Korsmeyer. Science Vol.270 pp. 96-99